Dynamin-related protein 1 (Drp1) inhibitor, inhibits Drp1 GTPase activity. Displays no effect on dynamin 1 or other mitochondrial dynamics-related proteins. Inhibits mitochondrial fission, dysfunction and reactive oxygen species (ROS) production in vitro. Reduces programmed cell death and improves cell viability by protecting mitochondrial integrity. Reduces mitochondrial fragmentation and mitochondrial ROS production in mouse model of Parkinson's disease. Cell permeable.

Vazegepant 是第一个用于急性治疗偏头痛的鼻内 gepant，并已宣布进行积极的 II/III 期研究。

埃莫西平是一种抗抑郁药。埃莫西平（2-乙基-6-甲基-3-羟基吡啶盐酸盐）和美西多（2-乙基-6-甲基-3-羟基吡啶琥珀酸盐）对外周血脂质过氧化产物含量的影响研究了中老年腹主动脉粥样硬化患者胃肠道病理临床症状的动态变化。